Spinal cord injury disrupts the axonal connection between the brain and the spinal cord below the lesion, contributing to unrecoverable functional deficits. A long term interest of my lab is to develop novel repair strategies to promote axon regeneration and restore lost function. Towards this, our research are focusing on the following questions: (1). Why injured axons fail to regenerate and how to promote axon regeneration? (2). How to increase the functionality of regenerated or spared axons after injury? I will present our recent results on each of these fronts.
Juana María Pasquini